RAD51 UP-REGULATION® is a dietary supplement specially indicated for preserving genomic integrity by amplifying the protein that directs homologous DNA repair: RAD51.
RAD51 UP-REGULATION® contains the active fraction RAD 51 -UP® from Tahitian Vanilla (Vanilla tahitensis) and Zinc. RAD51 UP-REGULATION® enables complete and faithful repair of DNA double-strand breaks. Homologous DNA repair is impaired in BRCA1 and BRCA2 mutation carriers.
This supplementation helps restore the levels of proteins involved in DNA repair and also normalises immune and antioxidant functions.
A weakened immune system is more susceptible to environmental viruses and bacteria. Certain vitamins, antioxidants and minerals are known to contribute to the proper functioning of the immune system. Zinc is one of the trace elements essential for good health, in particular by enabling normal protein and DNA synthesis and helping to preserve genomic integrity.
FORM AND PRESENTATION:
Box of 45 tablets of 500 mg.
WHO IS RAD51 UP-REGULATION® PRIMARILY INTENDED FOR?
This dietary supplement is indicated for preserving genomic integrity:
Women and men carrying a BRCA1, BRCA2 mutation: genes that produce proteins that help repair damaged DNA; or over expressing MSHI: microsatellite instability predisposing to mutations. BRAC1 and BRAC2 are the guardians of our genome.
Alternates with DNA-PKASE®Inhibat.
In addition to MILACTIF® 200 against cell loss.
THE STRENGTH OF RAD51 UP-REGULATION®: Quality and Innovation
The quality of Texinfine Laboratory products is our top priority.
The commitments of Texinfine Laboratory:
Environmental: Our plant extracts come from plants grown without harming natural resources.
Quality: Quality control is carried out on the plant material to monitor the presence of undesirable substances: heavy metals, aflatoxins, cytotoxicity, etc.
Innovation: We have designed and developed our own ingredients, guaranteeing unique active formulas based on extracts of natural origin.
Effectiveness: Each batch is checked in our laboratories to adjust the quantity of extract according to the biological activity of the ingredients. In our laboratories, Vanilla tahitensis extract (EVT) and specifically the RAD51-UP® fraction stimulates Rad51 expression in a dose-dependent manner (4 to 7 times) by transcription of the gene carried on the homologous chromosome.
Genome stability and integrity
Genome stability is a fundamental characteristic of living beings. Maintaining genome stability is essential to us all. Instability leads to progressive general dysfunction. DNA double-strand breaks are toxic lesions for the future of a cell. They can be generated by exogenous sources (exposure to radiation, chemical molecules, etc.) or endogenous sources (inflammation, genomic mutation, repair misdirection, depression, repeated exposure to infections or anxiety-provoking situations, etc.).
To repair damage to both DNA strands, there are two types of repair: Non-homologous repair or NHEJ and homologous repair or HR.
Non-homologous repair or NHEJ. Non-homologous repair is an economical repair method that is fast and simple, but dangerous for cell fate. NHEJ is controlled by DNA-PKcs.
Homologous repair or HR. Homologous repair or HR is a true repair that offers a serene future for cells. Homologous repair (HR) is initiated by a RAD51 protein encoded by the BRCA1 and BRCA genes. Homologous repair preserves genetic information.
